Activity

The Activity tab offers a timeline of case actions and enables users to leave comments. It supports key functions that enhance case management and review:

• Traceability—Maintains a complete, time-stamped history of case actions

• Error recovery—Allows users to identify and trace changes, such as variant edits or disease associations, made in error

• Real-time collaboration – Enables teams to monitor each other’s updates as they happen, ensuring transparency

• Training & quality control – Helps identify patterns in variant interpretation and supports consistent application of evidence criteria

• Audit compliance – Supports clinical and laboratory documentation standards (e.g., CAP/CLIA) by providing a verifiable action history

Each activity entry includes:

• Timestamp (date + time)

• User name of the person who performed the action

• Action description

Activity logs are kept for at least six years for full traceability.

The Activity tab logs the following actions:

Category	Activities
Case-related	Case created Case status changed Case participants updated Case labels modified Report created Case moved to trash Case data edited, no reanalysis initiated Case data edited and reanalysis launched
Comments	Comments left in the Activity tab
Variant tagging	Variant tag updated — this log entry includes a link to the relevant variant page for immediate review
Evidence notes	Evidence notes updated — this log entry includes a link to the relevant variant page for immediate review
Evidence pathogenicity	Variant pathogenicity updated — this log entry includes a link to the relevant variant page for immediate review
Evidence graph	Evidence graph updated — this log entry includes a link to the relevant variant page for immediate review
ACMG pathogenicity	ACMG evidence updated (logs any changes made via the ACMG classification wizard) — this log entry includes a link to the relevant variant page for immediate review
Transcript changes	Reference transcript updated

Viewing activity logs

In the Cases table, the Activity tab within the Case details panel displays only comments and case-related activities. To view the full list of all activities, open the Case details panel directly from the individual case page.

Important notes

1. Edits are permanent. Even if a change is undone, the original action remains recorded for traceability

2. Logs are case-specific. Activity entries do not reflect changes made in other cases or in the Curate database

3. Time zone awareness. Timestamps follow the system’s configured time zone, which may differ from your local time—especially in international collaborations.