Curate Variant annotations in the case
If the variant is already in your Curate database, you will see an Open Curate button on the Variant page Top bar.
Curate Variant annotations allow you to see if a variant already exists in your Curate database, access its stored pathogenicity, and view related data across multiple sections of the Variant Page. This ensures consistent interpretation and faster decision-making.
How do I know if the variant is already in Curate?
The top bar of the Variant Page features a dropdown menu with three options:
Open – Available if the variant already exists in your Curate database.
Add – Available if the variant does not exist in Curate; use it to add the variant directly to Curate.
Update – Available if the variant exists but has new notes, interpretation, or pathogenicity to sync.
Each option is enabled or disabled based on the variants' status in the Curate database.
Curate annotations are displayed across multiple locations in the Variant Page and Variant Table:
Where can I find Curate annotations?
Variant table > Known Variants column > 👁️ Curate Pathogenicity badge
Variant page > Visualization section > 👁️ Curate and CurateSV Curated data tracks (make sure to enable tracks of interest)
Warnings:
When exporting a variant from Analyze to Curate, users may sometimes see the error: &#xNAN;“None is not allowed for pathogenicity.” Check the variant type. This can be caused by unsupported variant types.
Curate annotations are only displayed if user roles allow access to Curate data.
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